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PRP Therapy for Joint, Tendon, and Muscle Recovery

Platelet-rich plasma or PRP therapy revolutionizes orthopedic and musculoskeletal care, offering a noninvasive option for natural healing and recovery.

PRP Therapy

Written by

Angel Rigueras

Pain Management Specialist

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Written by

Angel Rigueras

Pain Management Specialist

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Table of content

Table of Content

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PRP Therapy is designed to accelerate tissue repair and reduce pain, PRP has become a go-to treatment for individuals seeking effective solutions for injuries and chronic conditions.

This blog will explain PRP therapy, its composition and benefits, the conditions it treats, such as tendon and ligament injuries (TLI) and joint and muscle injuries, and how the process works at UOC. You will also discover why PRP might be the ideal solution for your recovery journey.

PRP therapy - Blood composition

What is PRP and Where Does It Come From?

Platelet-Rich Plasma therapy is derived from the patient’s own blood, offering a natural and non-surgical option for healing. PRP consists of two key components: plasma, the liquid portion of blood, and platelets, a type of blood cell critical for clotting and tissue repair. Platelets also contain growth factors, which play a vital role in stimulating cell reproduction and accelerating tissue regeneration. 

The process of creating PRP begins with a simple blood draw. The sample is then placed into a centrifuge, a machine that spins the blood rapidly to separate its components. This process concentrates the platelets within the plasma while removing red and white blood cells, which can contribute to inflammation. The resulting platelet-rich solution is then prepared for injection.

Once prepared, the PRP is injected directly into the targeted area, such as an injured joint, tendon, or muscle. In some cases, ultrasound guidance is used to ensure precision. The primary goal is to increase the concentration of growth factors in the injured area, enhancing the body’s natural healing response. Studies suggest that PRP can shorten recovery time, reduce pain, and promote faster tissue regeneration.

It is important to note that PRP therapy is not the same as stem cell therapy. However, the two treatments can be complementary. While PRP focuses on delivering growth factors to stimulate tissue repair, stem cells can further enhance the regeneration process by differentiating into new cells. This combination can provide powerful results in certain cases, offering patients an advanced and comprehensive approach to recovery.

A Revolutionary Treatment For Sports Injuries

Injuries to joints, tendons, and muscles are common, especially among athletes, and can occur due to overuse, acute trauma, or sports-related activities.

Muscle strains, for example, account for a significant portion of athletic injuries, with prevalence rates ranging from 12% to 16%.

Specific muscle groups, such as the hamstrings, quadriceps, and gastrocnemius, are particularly vulnerable due to their role in dynamic movements and their crossing of multiple joints. 

These injuries not only cause immediate pain and loss of mobility but are also prone to re-injury, with recurrence rates ranging from 12% to 21%.

This pattern is evident across sports like football, rugby, and track and field, where re-injury rates can exceed 30% in some leagues. Such injuries result in lost playing time, significant physical setbacks, and high costs associated with prolonged recovery.

Timely and personalized care is essential to prevent chronic complications and support effective recovery from these injuries. Clinical research and imaging studies highlight PRP’s ability to accelerate recovery, alleviate pain, and reduce swelling, making it a transformative option for managing these challenging conditions.

PRP For TLIs

PRP therapy shows promise in treating both acute and chronic tendon injuries, including conditions like Achilles tendinopathy, elbow tendinopathy, and patellar tendinopathy.

In cases of chronic Achilles tendinopathy, PRP has demonstrated significant improvements in clinical scores and tendon function. Similarly, PRP injections for elbow tendinopathy have consistently outperformed traditional treatments like corticosteroids, offering longer-lasting pain relief and functional improvements.

For ligament injuries, such as ACL tears, PRP enhances vascularization during reconstruction, potentially improving knee stability and healing outcomes. Despite some variability in study results, PRP continues to be a valuable adjunct in sports medicine for accelerating recovery and restoring function.

Muscle Recovery

A Closer Look at PRP's Key Healing Agents

PRP works by delivering a concentrated dose of platelets and growth factors directly to the injury site, including:

  • Platelet-derived growth Factor (PDGF) to promote cell proliferation,

     

  • Transforming Growth Factor-Beta (TGF-β) to stimulate collagen production,

     

  • Vascular Endothelial Growth Factor (VEGF) to enhance blood supply,

     

  • and Epidermal Growth Factor (EGF) to support tissue regeneration.

     

  • Additionally, Insulin-Like Growth Factor-I (IGF-I) aids in protein synthesis,

     

  • Fibroblastic Growth Factor (FGF) fosters connective tissue formation,

     

  • and Hepatocyte Growth Factor (HGF) reduces inflammation and supports remodeling.

These growth factors accelerate healing, improve collagen alignment to better mimic natural tissue, reduce scar formation, and lower the risk of re-injury. PRP also includes antimicrobial peptides, boosting its ability to protect against infections.

Together, these components create an environment that accelerates repair, improves tissue strength, and supports the body’s natural healing processes for tendon and ligament recovery.

The Benefits of PRP for Joint, Tendon, and Muscle Recovery

Platelet-rich plasma or PRP therapy offers a range of advantages for recovering from TLIs.

Here are the most noticeable benefits:

Accelerates Recovery and Reduces Pain

  • PRP shortens recovery times by promoting faster tissue repair and regeneration, particularly in acute injuries like hamstring or adductor strains. Studies have reported up to a 7-day reduction in recovery time compared to traditional therapies.

  • Patients often experience less pain during rehabilitation and a smoother progression through recovery phases.

Enhances Tissue Strength and Alignment

  • PRP stimulates fibroblast proliferation, which boosts collagen production, improving the strength and structural integrity of tendons and ligaments.

  • Mechanical loading combined with PRP therapy aligns collagen fibers, promoting flexibility and durability of the treated tissues.

Reduces Risk of Re-injury

  • By supporting the natural tissue healing process and improving the biomechanical properties of the repaired areas, PRP lowers the chances of re-injury.

Promotes Angiogenesis and Nutrient Delivery

  • Growth factors like Endothelial Growth Factor (EGF) in PRP promote angiogenesis, ensuring better oxygen and nutrient delivery to the injured site. This supports faster and more effective healing.

Works Naturally and Safely

  • PRP uses the patient’s blood, eliminating the risk of allergic reactions or artificial residuals in the body.

  • This natural approach ensures a biocompatible, minimally invasive therapy that is safe for most patients.

Age-Specific Benefits

  • PRP’s efficacy tends to be higher in younger individuals due to higher levels of healing-capable stem cells. However, tailored protocols for older patients can still deliver significant improvements in tissue repair.

A Non-Surgical Option

  • PRP therapy is a fast and effective alternative to surgery and It complements other therapies and supports healing. With a prompt process that avoids unnecessary steps and does not require insurance approval, PRP enables patients to quickly start healing with minimal downtime.

Integration with Other Therapies

  • PRP can work alongside treatments like stem cell therapy to provide a comprehensive regenerative approach, combining their strengths to address complex injuries.

At UOC, our patient-first approach ensures that you receive tailored PRP therapy for your specific needs, optimizing your recovery journey.

How to Diagnose PRP as a Suitable Treatment

At University Orthopedic Care, determining whether PRP therapy is the right choice begins with a comprehensive evaluation of your condition. Our expert team utilizes advanced diagnostic tools and personalized assessments to ensure the most effective treatment plan for your needs.

Advanced Diagnostic Imaging

  • Magnetic Resonance Imaging (MRI) and ultrasound (US) are essential tools in confirming muscle, tendon, or ligament injuries. These imaging techniques allow our specialists to precisely locate areas of edema and structural abnormalities, ensuring PRP is applied directly to the site that needs healing.

Personalized Assessment

  • No two injuries are the same. UOC avoids a one-size-fits-all approach by tailoring every PRP treatment plan to the individual patient. This includes assessing the severity and type of injury, your overall health, and recovery goals.

Ideal Cases for PRP

  • PRP therapy is especially effective for recent injuries, acute pain, and cases where non-surgical options are preferred. Whether it’s a muscle strain, joint issue, or ligament injury, PRP can accelerate recovery and reduce discomfort.

By combining state-of-the-art imaging with a patient-first philosophy, UOC ensures PRP therapy is not only suitable but also maximized for the best possible outcomes. If you’re experiencing acute pain or recovering from a recent injury, PRP may be the ideal solution for your recovery.

What to Expect During Your PRP Journey at UOC

We prioritize your comfort and ensure you’re well-informed every step of the way during your Platelet-Rich Plasma (PRP) therapy. Here’s a comprehensive guide to what you can expect before, during, and after your treatment.

Before Your PRP Therapy

Your journey begins with a consultation where our specialists explain the procedure and tailor a plan to meet your specific needs. To prepare for your session, it’s essential to follow these pre-procedure guidelines:

  • Discontinue certain medications:
    • Stop anti-inflammatory medications at least five days before your procedure.

    • Pause any blood-thinning herbs or supplements one week before.

    • Avoid systemic steroids for one to two weeks before your session.

    • Cease steroid injections at least one month before treatment.
    •  
  • On the day of your procedure:
    • Eat a nutritious meal.

    • Stay hydrated by drinking plenty of water.

If you are on chronic oral steroids or other long-term medications, discuss a discontinuation plan with your primary care provider to ensure a safe transition. Always consult your prescribing doctor before making changes to your medication regimen.

After Your PRP Therapy

Following your session, your body will begin the natural healing process enhanced by PRP. To maximize the benefits of your treatment, adhere to the following guidelines:

First 3 Days Post-Treatment

  • Movement: Limit the use of the treated area, but light movement is encouraged to aid recovery.

  • Hydration: Drink plenty of water to support healing.

  • Medication Avoidance: Do not take anti-inflammatory medications, blood-thinning supplements, or steroids unless directed by your physician.

  • Avoid the following:
    • Ice or heat application to the injection site.

    • Hot baths, saunas, or soaking the area for 24 hours.

    • Alcohol consumption or smoking.

Weeks 1–4 Post-Treatment

  • Gradually increase daily activities as tolerated.

  • Begin incorporating light exercises that your UOC care team recommends to support recovery.

  • Apply ice for 15–20 minutes, 3–4 times a day if needed for comfort.

  • If directed, you may resume anti-inflammatory medications for pain management.

  • Continue avoiding alcohol, smoking, and excessive caffeine to optimize healing.

Ongoing Recovery and Follow-Up

By the fifth week post-treatment, physical therapy is highly encouraged to further strengthen and rehabilitate the treated area.

We will schedule a follow-up appointment to assess your progress, adjust your treatment plan as necessary, and ensure your recovery is on track.

Even if you feel great, attending your follow-up visit is essential to achieving the best possible outcome.

Why Choosing UOC

At University Orthopedic Care (UOC), our PRP therapy leverages top-notch technology to provide patients with the most advanced regenerative treatment available.

This innovative approach offers a highly concentrated form of Platelet-Rich Plasma (PRP) that supports faster healing, enhanced recovery, and long-term relief for a variety of orthopedic conditions. Here’s what makes our PRP therapy stand out:

  • Optimized Composition for Maximum Healing: Our PRP contains essential growth factors like PDGF, VEGF, and TGF-β to promote tissue repair, stimulate blood vessel growth, and enhance collagen production.

  • Tailored Inflammatory Control: UOC customizes PRP treatments for each patient’s needs, using precise inflammatory responses to target specific conditions like infected wounds or joint injuries.

  • Advanced Platelet Concentration: Exceeding clinical standards, our PRP provides potent growth factors and cytokines to accelerate recovery and relieve pain.

  • Convenient and Non-Invasive: This minimally invasive procedure is performed quickly with precise guidance, requiring no downtime and supporting seamless outpatient recovery.

  • Lasting Results: PRP jump-starts a natural healing process that continues to improve tissue health, pain relief, and mobility over weeks and months.

UOC’s approach to PRP therapy represents our commitment to providing patients with transformative, evidence-based care that promotes healing and helps them return to an active, pain-free lifestyle.

Conclusion

Platelet-rich plasma or PRP therapy offers a natural, revolutionary solution for joint, tendon, and muscle recovery.

By harnessing the body’s regenerative capabilities, PRP potentiates faster healing, reduces discomfort, and supports long-term recovery for a wide range of orthopedic conditions.

Whether addressing sports injuries, aiding in tissue repair, or enhancing non-surgical treatment plans, PRP has become a transformative option for patients seeking effective and minimally invasive care.

 

At University Orthopedic Care, we prioritize our patients’ needs, ensuring swift and effective assistance, and avoiding unnecessary delays. Our streamlined approach ensures that PRP therapy is accessible and prompt, focusing on what truly matters: your recovery and well-being.

 

If you’re ready to explore how PRP therapy can help you regain mobility, reduce pain, and achieve a healthier, more active lifestyle, contact UOC today at (866) 962-1744 to schedule your consultation.

Let us help you take the next step toward recovery and a better quality of life.